Publications 2015

Englert, M., Nakamura, A., Wang, Y-S., Söll, D. and Guo, L-T. (2015) Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog. Nucleic Acids Res. 43, 11061-11067. Abstract

Amiram, M., Haimovich, A.D., Fan, C., Wang, Y.S., Aerni, H.R., Ntai, I., Moonan, D.W., Ma, N.J., Rovner, A.J., Hong, S.H., Kelleher, N.L., Goodman, A.L., Jewett, M.C., Söll, D., Rinehart, J. and Isaacs, F.J. (2015) Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids. Nat. Biotechnol. 33, 1272-1279. Abstract

Ling, J., O.Donoghue, P. and Söll, D. (2015) Genetic code flexibility in microorganisms: novel mechanisms and impact on bacterial physiology. Nat. Rev. Microbiol. 13, 707-721. Abstract

Hoesl, M.G., Oehm, S., Durkin, P., Darmon, E., Peil, L., Aerni, H-R., Rappsilber, J., Rinehart, J., Leach, D., Söll, D. and Budisa, N. (2015) Chemical evolution of a bacterial proteome. Angew. Chem. Int. Ed. Engl. 54, 10030-10034. Abstract

Fan, C., Xiong, H., Reynolds, N. and Söll, D. (2015) Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acids. Nucleic Acids Res. 43 (22), e156. Abstract

Miller, C., Bröcker, M.J., Prat, L., Ip, K., Chirathivat, N., Feiock, A., Veszpremi, M. and Söll, D. (2015) A synthetic tRNA for EF-Tu mediated selenocysteine incorporation in vivo and in vitro. FEBS Lett. 589, 2194-2199. Abstract

Quax, T.E.F., Claassens, N.J., Söll, D. and van der Oost, J. (2015) Codon bias as a means to fine-tune gene expression. Mol. Cell 59, 149-161. Abstract

Anttonen, A-K., Hilander, T., Linnankivi, T., Isohanni, P., French, R., Liu, Y., Simonovi., M., Söll, D., Somer, M., Muth-Pawlak, D., Corthals, G.L., Laari, A., Ylikallio, E., Lähde, M., Valanne, L., Lönnqvist, T., Pihko, H., Paetau, A., Lehesjoki, A-E., Suomalainen, A. and Tyynismaa, H. (2015) Selenoprotein biosynthesis defect mimicking mitochondrial encephalohepatopathy. Neurology, 85, 306-315. Abstract

Söll, D. (2015) A tRNA-guided research journey from synthetic chemistry to synthetic biology. RNA 21, 742-744. Abstract

Polikanov, Y.S., Melnikov, S.V., Söll, D. and Steitz, T.A. (2015) Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly. Nat. Struct. Mol. Biol. 22, 342-344. Abstract

Suzuki, T., Nakamura, A., Kato, K., Söll, D., Tanaka, I., Sheppard, K. and Yao, M. (2015) Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis. Proc. Natl. Acad. Sci. USA 112, 382-387. Abstract