Publications 2009

Heinemann,I.U., O’Donoghue, P., Madinger, C., Benner, J., Randau, L., Noren, C.J. and Söll, D. (2009) The appearance of pyrrolysine in tRNAHis guanylyltransferase by neutral evolution. Proc. Natl. Acad. Sci. USA 106, 21103-21108. Abstract


Alkalaeva, E., Eliseev, B., Ambrogelly, A., Vlasov, P., Kondrashov, F.A., Gundllapalli, S., Frolova, L., Söll, D. and Kisselev, L. (2009) Translation termination in pyrrolysine-utilizing archaea. FEBS Lett. 583, 3455-3460. Abstract


Araiso, Y., Sherrer, R.L., Ishitani, R., Ho, J.M.L., Söll, D. and Nureki, O. (2009) Structure of a tRNA-dependent kinase essential for selenocysteine decoding. Proc. Natl. Acad. Sci. USA 106, 16215-16227. Abstract


Mitchell, M., Xue, S., Erdman, R., Randau, L., Söll, D. and Li, H. (2009) Crystal structure of the functional Nanoarchaeum equitans tRNA splicing endonuclease. Nucl. Acids Res. 37, 5793-5802. Abstract


Palioura, S., Sherrer, R.L., Steitz, T.A., Söll, D. and Simonovic, M. (2009) The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation. Science 325, 321-325. Abstract


Wu, J., Bu, W., Sheppard, K., Kitabatake, M., Kwon, S-T., Söll, D. and Smith, J.L. (2009) Insights into tRNA-dependent amidotransferase evolution and catalysis from the structure of the Aquifex aeolicus enzyme. J. Mol. Biol. 391, 703-716. Abstract


Randau, L., Stanley, B.J., Kohlway, A., Mechta, S., Xiong, Y. and Söll, D. (2009) A cytidine deaminase edits C-to-U in transfer RNAs in archaea. Science 324, 657-659. Abstract


Charriere, F., O’Donoghue, P., Helgadóttir, S., Marechal-Drouard, L., Cristodero, M., Horn, E.K., Söll, D. and Schneider, A. (2009) Dual targeting of a tRNAAsp requires two different aspartyl-tRNA synthetases in Trypanosoma brucei. J. Biol. Chem. 284, 16210-16217. Abstract


Aeby, E., Palioura, S., Pusnik, M., Marazzia, J., Lieberman, A., Ullu, E., Söll, D. and Schneider, A. (2009) The canonical pathway for selenocysteine insertion is dispensable in Trypanosomes. Proc. Natl. Acad. Sci. USA 106, 5088-5092. Abstract


Nozawa, K., O’Donoghue, P., Gundllapalli, S., Araiso, Y., Ishitani, R., Umehara, T., Söll, D. and Nureki, O. (2009) Pyrrolysyl-tRNA synthetase-tRNAPyl structure reveals the molecular basis of orthogonality. Nature 457, 1163-1167. Abstract


Su, D., Hohn, M., Palioura, S., Sherrer, R.L., Yuan, J., Söll, D. and O’Donoghue, P. (2009) How an obscure archaeal gene inspired the discovery of selenocysteine biosynthesis in humans. IUBMB Life 61, 35-39. Abstract